Drinking water must be safe for the health of the people who consume it. The quality of drinking water consists of physico-chemical and microbiological parameters. In order to preserve the microbiological integrity of drinking water, it is necessary to continuously monitor the source and the distribution network, as well as maintain them. Disinfection of raw water by chlorination is also necessary. The aim of this work is to examine the physico-chemical and microbiological parameters of drinking water and indicate risk analysis, control measures that can affect the prevention and elimination of pollution in order to maintain the microbiological integrity of drinking water in the city of Zrenjanin.